Advertisement
Review Article| Volume 45, ISSUE 1, P129-136, January 2018

Risk-Reducing Mastectomy and Breast Reconstruction

Indications and Evidence for Current Management Strategies
  • Author Footnotes
    1 Present address: 5925 Almeda Road, Unit 1-1815, Houston, TX 77004.
    Bradley S. Eisemann
    Footnotes
    1 Present address: 5925 Almeda Road, Unit 1-1815, Houston, TX 77004.
    Affiliations
    Department of General Surgery, Division of Plastic Surgery, Baylor College of Medicine, 6701 Fannin Street, Suite 620, Houston, TX 77030, USA
    Search for articles by this author
  • Aldona J. Spiegel
    Correspondence
    Corresponding author.
    Affiliations
    Weil Cornell Medicine, Center for Breast Restoration, Department of Surgery, Houston Methodist Hospital, Houston Methodist Institute for Reconstructive Surgery, 6560 Fannin Street, Suite 2200, Houston, TX 77030, USA
    Search for articles by this author
  • Author Footnotes
    1 Present address: 5925 Almeda Road, Unit 1-1815, Houston, TX 77004.
Published:September 29, 2017DOI:https://doi.org/10.1016/j.cps.2017.08.013

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Plastic Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Greenlee R.
        Cancer statistics, 2001.
        CA Cancer J Clin. 2001; 51: 15-36
        • Siegel R.
        • Miller K.
        • Jemal A.
        Cancer statistics, 2015.
        CA Cancer J Clin. 2015; 65: 5-29
        • Benson J.
        • Dumitru D.
        • Malata C.
        Oncologic safety of conservative mastectomy in the therapeutic setting.
        Gland Surg. 2016; 5: 37-46
      1. NCCN. NCCN clinical practice guidelines in oncology, breast cancer risk reduction. 2016. Available at: https://www.nccn.org/professionals/physician_gls/pdf/breast_risk.pdf. Accessed June 4, 2016.

        • Hartmann L.
        • Radisky D.
        • Frost M.
        • et al.
        Understanding the premalignant potential of atypical hyperplasia through its natural history: a longitudinal cohort study.
        Cancer Prev Res (Phila). 2014; 7: 211-217
        • Travis L.
        • Hill D.
        • Dores G.
        • et al.
        Cumulative absolute breast cancer risk for young women treated for Hodgkin lymphoma.
        J Natl Cancer Inst. 2005; 97: 1428-1437
        • Gail M.
        • Brinton L.
        • Byar D.
        • et al.
        Projecting individualized probabilities of developing breast cancer for white females who are being examined annually.
        J Natl Cancer Inst. 1989; 81: 1879-1886
        • Gail M.
        Validation studies on a model for breast cancer risk.
        J Natl Cancer Inst. 1994; 86: 573-575
      2. Project NCIaNSABaB. Breast cancer risk assessment tool. Available at: http://www.cancer.gov/bcrisktool/. Accessed June 1, 2016.

        • Ernster V.
        Prophylactic mastectomy in women with a high risk of breast cancer.
        N Engl J Med. 1999; 340: 1838
        • Roukas D.
        Role of surgery in the prophylaxis of hereditary cancer syndromes.
        Ann Surg Oncol. 2002; 9: 607-609
        • Murthy V.
        • Chamberlain R.
        Prophylactic mastectomy in patients at high risk: is there a role for sentinel lymph node biopsy?.
        Clin Breast Cancer. 2013; 13: 180-187
        • Hartmann L.
        • Stllers T.
        • Schaid D.
        Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers.
        J Natl Cancer Inst. 2001; 93: 1633-1637
        • Meijers-Heijboer H.
        • van Geel B.
        • van Putten W.
        Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation.
        N Engl J Med. 2001; 345: 159-164
        • Rebbeck T.
        • Friebel T.
        • Lynch H.
        • et al.
        Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.
        J Clin Oncol. 2004; 22: 1055-1062
        • Hartmann L.
        • Schaie D.
        • Woods J.
        • et al.
        Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer.
        N Engl J Med. 1999; 340: 77-84
        • Meijers-Heijboer H.
        • Brekelmans C.
        • Menke-Pluymers M.
        • et al.
        Use of genetic testing and prophylactic mastectomy and oophorectomy in women with breast or ovarian cancer from families with a BRCA1 or BRCA2 mutation.
        J Clin Oncol. 2003; 21: 1675-1681
        • Geiger A.
        • Yu O.
        • Herrington L.
        • et al.
        A population-based study of bilateral prophylactic mastectomy efficacy in women at elevated risk for breast cancer in community practices.
        Arch Intern Med. 2005; 165: 516-520
        • Hamm R.
        • Lawler F.
        • Scheid D.
        Prophylactic mastectomy in women with a high risk of breast cancer: correspondence.
        N Engl J Med. 1999; 320: 137-139
        • van Dijk S.
        • Otten W.
        • Zoeteweij M.
        • et al.
        Genetic counselling and the intention to undergo prophylactic mastectomy: effects of a breast cancer risk assessment.
        Br J Cancer. 2003; 88: 1675-1681
        • Metcalfe K.
        Breast cancer risk perception among women who have undergone prophylactic bilateral mastectomy.
        J Natl Cancer Inst. 2002; 94: 1564-1569
        • Stefanek M.
        Predictors of and satisfaction with bilateral prophylactic mastectomy.
        Prev Med. 1995; 24: 412-419
        • Lopez M.
        • Porter K.
        The current role of prophylactic mastectomy.
        Surg Clin North Am. 1996; 76: 231-242
        • Herrinton L.
        • Barlow W.
        • Yu O.
        • et al.
        Efficacy of prophylactic mastectomy in women with unilateral breast cancer: a cancer research network project.
        J Clin Oncol. 2005; 23: 4275-4286
        • Peralta E.
        Contralateral prophylactic mastectomy improves the outcome of selected patients undergoing mastectomy for breast cancer.
        Am J Surg. 2000; 180: 439-445
        • Bilimoria M.
        • Maorrow M.
        The woman at increased risk for breast cancer: evaluation and management strategies.
        CA Cancer J Clin. 1995; 45: 263-278
        • Barry P.
        • Johnson R.
        • Harkenrider M.
        • et al.
        Contralateral prophylactic mastectomy: clinical and pathological features from a prospective database.
        Am J Med Sci. 2012; 344: 452-456
        • Hoover D.
        • Paragi P.
        • Santoro E.
        • et al.
        Prophylactic mastectomy in high risk patients: a practice-based review of the indications. Do we follow guidelines?.
        Breast Dis. 2010; 31: 19-27
        • Nekhlyudov L.
        • Bower M.
        • Herrinton L.
        • et al.
        Women's decision-making roles regarding contralateral prophylactic mastectomy.
        J Natl Cancer Inst Monogr. 2005; : 55-60
        • King T.
        • Gurevich I.
        • Sakr R.
        • et al.
        Occult malignancy in patients undergoing contralateral prophylactic mastectomy.
        Ann Surg. 2011; 254: 2-7
        • Mallon P.
        • Feron J.
        • Couturaud B.
        • et al.
        The role of nipple-sparing mastectomy in breast cancer: a comprehensive review of the literature.
        Plast Reconstr Surg. 2013; 131: 969-984
        • Vlajcic Z.
        • Zic R.
        • Stanec S.
        • et al.
        Nipple-areola complex preservation: predictive factors of neoplastic nipple-areola complex invasion.
        Ann Plast Surg. 2005; 55: 240-244
        • Rusby J.
        • Brachtel E.
        • Othus M.
        • et al.
        Development and validation of a model predictive of occult nipple involvement in women undergoing mastectomy.
        Br J Surg. 2008; 95: 1356-1361
        • Weidong L.
        • Shuling W.
        • Xiaojing G.
        • et al.
        Nipple involvement in breast cancer: retrospective analysis of 2323 consecutive mastectomy specimens.
        Int J Surg Pathol. 2011; 19: 328-334
        • Brachtel E.
        • Rusby J.
        • Michaelson J.
        • et al.
        Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens.
        J Clin Oncol. 2009; 27: 4948-4954
        • Tang R.
        • Coopey S.
        • Merrill A.
        • et al.
        Positive nipple margins in nipple-sparing mastectomies: rates, management, and oncologic safety.
        J Am Coll Surg. 2016; 222: 1149-1155