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Review Article| Volume 50, ISSUE 2, P347-355, April 2023

Modern Approaches to Breast Neurotization

Published:January 25, 2023DOI:https://doi.org/10.1016/j.cps.2022.10.003

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      References

        • Admoun C.
        • Mayrovitz H.
        Choosing mastectomy vs. Lumpectomy-With-Radiation: experiences of breast cancer Survivors.
        Cureus. 2021; 13e18433https://doi.org/10.7759/cureus.18433
        • Hamilton K.L.
        • Kania K.E.
        • Spiegel A.J.
        Post-mastectomy sensory recovery and restoration.
        Gland Surg. 2021; 10: 494-497https://doi.org/10.21037/gs.2020.03.22
        • Slezak S.
        • McGibbon B.
        • Dellon A.
        The sensational transverse rectus abdominis Musculocutaneous (TRAM) flap: return of sensibility after TRAM breast reconstruction.
        Ann Plast Surg. 1992; 28: 210-217
        • Laikhter E.
        • Shiah E.
        • Manstein S.M.
        • et al.
        Trends and characteristics of neurotization during breast reconstruction: perioperative outcomes using the American College of surgeons national Surgical quality improvement Program (ACS-NSQIP).
        J Plast Surg Hand Surg. 2021; : 1-7https://doi.org/10.1080/2000656X.2021.1973484
        • Dellon A.
        Somatosensory testing and Rehabilitation.
        Institute for Peripheral Nerve Surgery, 2000
        • Buck II, D.
        Breast anatomy, Embryology, and Congenital Defects. Review of Plastic surgery.
        Elsevier, 2016: 73-77
        • Sarhadi N.
        • Shaw-Dunn J.
        • Soutar D.
        Nerve supply of the breast with special reference to the nipple and areola: Sir Astley Cooper Revisited.
        Clin Anat. 1997; 10: 283-288
        • Mohan A.T.
        • Suchyta M.
        • Vyas K.S.
        • et al.
        A cadaveric Anatomical and histological study of recipient intercostal nerve Selection for sensory reinnervation in autologous breast reconstruction.
        J Reconstr Microsurg. 2021; 37: 136-142https://doi.org/10.1055/s-0040-1715878
        • Cakmakoglu C.
        • Knackstedt R.
        • Gatherwright J.
        • et al.
        Determining the precise anatomic location of the sensory nerves to the abdominal wall: Optimizing autologous innervation of abdominally based free flaps.
        J Plast Reconstr Aesthet Surg. 2021; 74: 641-643https://doi.org/10.1016/j.bjps.2020.11.019
        • Khan A.
        • Zhang J.
        • Sollazzo V.
        • et al.
        Sensory change of the reconstructed breast envelope after skin-sparing mastectomy.
        Eur J Surg Oncol. 2016; 42: 973-979https://doi.org/10.1016/j.ejso.2016.03.018
        • Blondeel P.N.
        • Demuynck M.
        • Mete D.
        • et al.
        Sensory nerve repair in perforator flaps for autologous breast reconstruction: sensational or senseless?.
        Br J Plast Surg. 1999; 52: 37-44
        • Ray W.Z.
        • Mackinnon S.E.
        Management of nerve gaps: autografts, allografts, nerve transfers, and end-to-side neurorrhaphy.
        Exp Neurol. 2010; 223: 77-85https://doi.org/10.1016/j.expneurol.2009.03.031
        • Safa B.
        • Jain S.
        • Desai M.J.
        • et al.
        Peripheral nerve repair throughout the body with processed nerve allografts: results from a large multicenter study.
        Microsurgery. 2020; 40: 527-537https://doi.org/10.1002/micr.30574
        • Vartanian E.D.
        • Lo A.Y.
        • Hershenhouse K.S.
        • et al.
        The role of neurotization in autologous breast reconstruction: can reconstruction restore breast sensation?.
        J Surg Oncol. 2021; 123: 1215-1231https://doi.org/10.1002/jso.26422
        • Spiegel A.J.
        • Menn Z.K.
        • Eldor L.
        • et al.
        Breast reinnervation: DIEP neurotization using the third anterior intercostal nerve. Plast Reconstr Surg Glob open.
        . 2013; 1: e72https://doi.org/10.1097/GOX.0000000000000008
        • Temple C.L.
        • Tse R.
        • Bettger-Hahn M.
        • et al.
        Sensibility following innervated free TRAM flap for breast reconstruction.
        Plast Reconstr Surg. 2006; 117 (discussion 2128-30): 2119-2127https://doi.org/10.1097/01.prs.0000218268.59024.cc
        • Shridharani S.M.
        • Magarakis M.
        • Stapleton S.M.
        • et al.
        Breast sensation after breast reconstruction: a systematic review.
        J Reconstr Microsurg. 2010; 26: 303-310https://doi.org/10.1055/s-0030-1249313
        • Weissler J.M.
        • Koltz P.F.
        • Carney M.J.
        • et al.
        Sifting through the evidence: a comprehensive review and analysis of neurotization in breast reconstruction.
        Plast Reconstr Surg. 2018; 141: 550-565https://doi.org/10.1097/PRS.0000000000004108
        • Gatherwright J.
        • Knackstedt R.
        • Djohan R.
        Anatomic targets for breast reconstruction neurotization: Past results and future Possibilities.
        Ann Plast Surg. 2019; 82: 207-212https://doi.org/10.1097/SAP.0000000000001733
        • Xia T.Y.
        • Scomacao I.
        • Djohan R.
        • et al.
        Neurotization does not Prolong operative time in free flap breast reconstruction.
        Aesthet Plast Surg. 2022; https://doi.org/10.1007/s00266-022-02833-7
        • Beugels J.
        • Bijkerk E.
        • Lataster A.
        • et al.
        Nerve coaptation improves the sensory recovery of the breast in DIEP flap breast reconstruction.
        Plast Reconstr Surg. 2021; 148: 273-284https://doi.org/10.1097/PRS.0000000000008160
        • Magarakis M.
        • Venkat R.
        • Dellon A.L.
        • et al.
        Pilot study of breast sensation after breast reconstruction: evaluating the effects of radiation therapy and perforator flap neurotization on sensory recovery.
        Microsurgery. 2013; 33: 421-431https://doi.org/10.1002/micr.22124
        • Momeni A.
        • Meyer S.
        • Shefren K.
        • et al.
        Flap neurotization in breast reconstruction with nerve allografts: 1-year clinical outcomes.
        Plast Reconstr Surg Glob Open. 2021; 9e3328https://doi.org/10.1097/GOX.0000000000003328
        • Djohan R.
        • Scomacao I.
        • Knackstedt R.
        • et al.
        Neurotization of the nipple-areola complex during implant-based reconstruction: Evaluation of early sensation recovery.
        Plast Reconstr Surg. 2020; 146: 250-254https://doi.org/10.1097/PRS.0000000000006976
        • Temple C.L.F.
        • Ross D.C.
        • Kim S.
        • et al.
        Sensibility following innervated free TRAM flap for breast reconstruction: Part II. Innervation improves patient-rated quality of life.
        Plast Reconstr Surg. 2009; 124: 1419-1425https://doi.org/10.1097/PRS.0b013e3181b98963
        • Lagergren J.
        • Edsander-Nord A.
        • Wickman M.
        • et al.
        Long-term sensibility following Nonautologous, immediate breast reconstruction.
        Breast J. 2007; 13: 346-351
        • Bijkerk E.
        • van Kuijk S.M.J.
        • Beugels J.
        • et al.
        Breast sensibility after mastectomy and implant-based breast reconstruction.
        Breast Cancer Res Treat. 2019; 175: 369-378https://doi.org/10.1007/s10549-019-05137-8
        • Peled A.W.
        • Peled Z.M.
        Nerve preservation and allografting for sensory innervation following immediate implant breast reconstruction.
        Plast Reconstr Surg Glob Open. 2019; 7e2332https://doi.org/10.1097/GOX.0000000000002332
        • Tevlin R.
        • Brazio P.
        • Tran N.
        • et al.
        Immediate targeted nipple-areolar complex re-innervation: Improving outcomes in immediate autologous breast reconstruction.
        J Plast Reconstr Aesthet Surg. 2021; 74: 1503-1507https://doi.org/10.1016/j.bjps.2020.11.021
        • Spiegel A.J.
        • Salazar-Reyes H.
        • Izaddoost S.
        • et al.
        A Novel method for neurotization of deep inferior epigastric perforator and superficial inferior epigastric artery flaps.
        Plast Reconstr Surg. 2009; 123: 29e-30ehttps://doi.org/10.1097/PRS.0b013e318194d257